Background: There are scarce evidences that evaluated the impact of periodontal disease on oral health-related\r\nquality of life (OHRQoL) taking marginal gingival alterations into consideration. Thus, this study aimed to verify the\r\nassociation between OHRQoL and gingival enlargement and gingival bleeding in subjects under fixed orthodontic\r\ntreatment (FOT).\r\nMethods: 330 participants under FOT for at least 6 months were examined by a single, calibrated examiner for\r\nperiodontal variables and dental aesthetic index. Socio-economic background, body mass index, time with\r\northodontic appliances, and use of dental floss were assessed by oral interviews. OHRQoL was evaluated using the\r\noral health impact profile (OHIP-14) questionnaire. The assessment of associations used unadjusted and adjusted\r\nPoisson regression models.\r\nResults: Higher impacts on the OHIP-14 overall were observed in subjects who presented higher levels of anterior\r\ngingival enlargement (RR 2.83; 95% CI 2.60-3.09), were non-whites (RR 1.29; 95% CI 1.15-1.45), had household\r\nincome lower than five national minimum wages (RR 1.85; 95% CI 1.30-2.61), presented body mass index > 25\r\n(RR 1.14; 95% CI 1.01-1.29), and showed a dental aesthetic index > 30 (RR 1.32; 95% CI 1.20-1.46).\r\nConclusions: Anterior gingival enlargement seems to influence the OHRQoL in subjects receiving orthodontic\r\ntreatment.
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